P110 GAMMA
\pˈiː wˈɒnhˈʌndɹədən tˈɛn ɡˈamə], \pˈiː wˈɒnhˈʌndɹədən tˈɛn ɡˈamə], \p_ˈiː w_ˈɒ_n_h_ˈʌ_n_d_ɹ_ə_d_ə_n t_ˈɛ_n ɡ_ˈa_m_ə]\
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An enzyme that catalyzes the conversion of phosphatidylinositol to phosphatidylinositol 3-phosphate. This is the first committed step in the biosynthesis of phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. This pathway is thought to play a critical role in DNA repair, V (D)J recombination and cell cycle checkpoints. EC 2.7.1.137.
By DataStellar Co., Ltd
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Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.