ORTHOCEPHALOUS
\ˈɔːθə͡ʊsfələs], \ˈɔːθəʊsfələs], \ˈɔː_θ_əʊ_s_f_ə_l_ə_s]\
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Platidiam
- An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.