\ˈɒpʃənə͡li], \ˈɒpʃənə‍li], \ˈɒ_p_ʃ_ə_n_əl_i]\

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bcr v abl Oncogene

  • Retrovirus-associated DNA sequences (abl) originally isolated from Abelson murine leukemia virus (Ab-MuLV). proto-oncogene abl (codes for a protein that member tyrosine kinase family. human c-abl gene is located at 9q34.1 on the long arm of chromosome 9. It activated by translocation to bcr 22 in chronic myelogenous leukemia.
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