OPTIC NEURITIDES
\ˈɒptɪk njˈuːɹɪtˌa͡ɪdz], \ˈɒptɪk njˈuːɹɪtˌaɪdz], \ˈɒ_p_t_ɪ_k n_j_ˈuː_ɹ_ɪ_t_ˌaɪ_d_z]\
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Inflammation of the optic nerve. Commonly associated conditions include autoimmune disorders such as MULTIPLE SCLEROSIS, infections, and granulomatous diseases. Clinical features include retro-orbital pain that is aggravated by eye movement, loss of color vision, and contrast sensitivity that may progress to severe visual loss, an afferent pupillary defect (Marcus-Gunn pupil), and in some instances optic disc hyperemia and swelling. Inflammation may occur in the portion of the nerve within the globe (neuropapillitis or anterior optic neuritis) or the portion behind the globe (retrobulbar neuritis or posterior optic neuritis).
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