OPIOID RECEPTOR
\ˈə͡ʊpɪˌɔ͡ɪd ɹɪsˈɛptə], \ˈəʊpɪˌɔɪd ɹɪsˈɛptə], \ˈəʊ_p_ɪ__ˌɔɪ_d ɹ_ɪ_s_ˈɛ_p_t_ə]\
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Cell membrane proteins that bind opioids and trigger intracellular changes which influence the behavior of cells. The endogenous ligands for opioid receptors in mammals include three families of peptides, the enkephalins, endorphins, and dynorphins. The receptor classes include mu, delta, and kappa receptors. Sigma receptors bind several psychoactive substances, including certain opioids, but their endogenous ligands are not known.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.