OMEGA AGATOXIN IVA
\ə͡ʊmˈe͡ɪɡəɹ ˈaɡɐtˌɒksɪn ˌa͡ɪvˌiːˈe͡ɪ], \əʊmˈeɪɡəɹ ˈaɡɐtˌɒksɪn ˌaɪvˌiːˈeɪ], \əʊ_m_ˈeɪ_ɡ_ə_ɹ ˈa_ɡ_ɐ_t_ˌɒ_k_s_ɪ_n ˌaɪ_v_ˌiː__ˈeɪ]\
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A neuropeptide toxin from the venom of the funnel web spider, Agelenopsis aperta. It inhibits CALCIUM CHANNELS, P-TYPE by altering the voltage-dependent gating so that very large depolarizations are needed for channel opening. It also inhibits CALCIUM CHANNELS, Q-TYPE.
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Word of the day
tinctura quininae ammoniata
- A preparation made by dissolving quinin sulphate in alcohol [Br. Ph.].