OLFACTORY NEUROBLASTOMA
\ɒlfˈaktəɹˌi njˌuːɹəblastˈə͡ʊmə], \ɒlfˈaktəɹˌi njˌuːɹəblastˈəʊmə], \ɒ_l_f_ˈa_k_t_ə_ɹ_ˌi n_j_ˌuː_ɹ_ə_b_l_a_s_t_ˈəʊ_m_ə]\
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A malignant olfactory neuroblastoma arising from the olfactory epithelium of the superior nasal cavity and cribriform plate. It is uncommon (3% of nasal tumors) and rarely is associated with the production of excess hormones (e.g., SIADH, Cushing Syndrome). It has a high propensity for multiple local recurrences and bony metastases. (From Holland et al., Cancer Medicine, 3rd ed, p1245; J Laryngol Otol 1998 Jul;112 (7):628-33)
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SQ10,643
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