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\ˈɒl twˈɛntisˈɛvən fˈɔːhˈʌndɹəd], \ˈɒl twˈɛntisˈɛvən fˈɔːhˈʌndɹəd], \ˈɒ_l t_w_ˈɛ_n_t_i_s_ˈɛ_v_ə_n f_ˈɔː_h_ˈʌ_n_d_ɹ_ə_d]\
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A cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation. (From Martindale, The Extra Pharmacopoeia, 30th ed).
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.