OFFICE OF INSPECTOR GENERAL
\ˈɒfɪs ɒv ɪnspˈɛktə d͡ʒˈɛnəɹə͡l], \ˈɒfɪs ɒv ɪnspˈɛktə dʒˈɛnəɹəl], \ˈɒ_f_ɪ_s ɒ_v ɪ_n_s_p_ˈɛ_k_t_ə dʒ_ˈɛ_n_ə_ɹ_əl]\
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Sporadic Retinoblastoma
- A malignant arising nuclear layer retina that is most primary eye in children. The tumor tends to occur early childhood or infancy present at birth. majority are sporadic, but condition may be transmitted as autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS; STRABISMUS; visual loss represent common clinical characteristics this condition. (From DeVita et al., Cancer: Principles Practice Oncology, 5th ed, p2104)
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