OBJECTIVE VERTIGO
\ɒbd͡ʒˈɛktɪv vˈɜːtɪɡˌə͡ʊ], \ɒbdʒˈɛktɪv vˈɜːtɪɡˌəʊ], \ɒ_b_dʒ_ˈɛ_k_t_ɪ_v v_ˈɜː_t_ɪ_ɡ_ˌəʊ]\
Definitions of OBJECTIVE VERTIGO
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ATP Binding Cassette, Sub Family B Proteins
- A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.