NONSUPPRESSIBLE INSULINLIKE ACTIVITY
\nˌɒnsəpɹˈɛsəbə͡l ˈɪnsuːlˌɪnla͡ɪk aktˈɪvɪti], \nˌɒnsəpɹˈɛsəbəl ˈɪnsuːlˌɪnlaɪk aktˈɪvɪti], \n_ˌɒ_n_s_ə_p_ɹ_ˈɛ_s_ə_b_əl ˈɪ_n_s_uː_l_ˌɪ_n_l_aɪ_k a_k_t_ˈɪ_v_ɪ_t_i]\
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A blood protein (NSILA) which mimics the biological activity of insulin in serum, but is not suppressed by insulin antibodies. During acid-ethanol extraction of Cohn fraction III, 10% of the activity is found in the supernatant (NSILA-S) and the remaining activity in the precipitate (NSILA-P). The latter is a large molecular compound, much less stable than the soluble fraction. NSILA-S is a more potent growth factor than insulin and exhibits sulfation activity.
By DataStellar Co., Ltd
Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.
Nearby Words
- nonsufficient funds check
- nonsuit
- nonsuited
- nonsuiting
- nonsupport
- Nonsuppressible Insulinlike Activity
- nonsuppurative
- nonsurety
- nonsurgical
- nonsweet
- nonsyllabic