NISSL DEGENERATION
\nˈɪsə͡l dɪd͡ʒˌɛnəɹˈe͡ɪʃən], \nˈɪsəl dɪdʒˌɛnəɹˈeɪʃən], \n_ˈɪ_s_əl d_ɪ_dʒ_ˌɛ_n_ə_ɹ_ˈeɪ_ʃ_ə_n]\
Definitions of NISSL DEGENERATION
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Pathologic changes that occur in the axon and cell body of a neuron proximal to an axonal lesion. The process is characterized by central chromatolysis which features flattening and displacement of the nucleus, loss of Nissl bodies, and cellular edema. Central chromatolysis primarily occurs in lower motor neurons.
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