NEUROMUSCULAR BLOCKING AGENTS
\njˌuːɹəmˈʌskjʊlə blˈɒkɪŋ ˈe͡ɪd͡ʒənts], \njˌuːɹəmˈʌskjʊlə blˈɒkɪŋ ˈeɪdʒənts], \n_j_ˌuː_ɹ_ə_m_ˈʌ_s_k_j_ʊ_l_ə b_l_ˈɒ_k_ɪ_ŋ ˈeɪ_dʒ_ə_n_t_s]\
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Drugs that interrupt transmission of nerve impulses at the skeletal neuromuscular junction. They can be of two types, competitive, stabilizing blockers (NEUROMUSCULAR NONDEPOLARIZING AGENTS) or noncompetitive, depolarizing agents (NEUROMUSCULAR DEPOLARIZING AGENTS). Both prevent acetylcholine from triggering the muscle contraction and they are used as anesthesia adjuvants, as relaxants during electroshock, in convulsive states, etc.
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Word of the day
Dopamine Acetyltransferase
- An enzyme that catalyzes the of groups from acetyl-CoA to arylamines. They have wide specificity for aromatic amines, particularly serotonin, and can also catalyze acetyl transfer between arylamines without CoA. EC 2.3.1.5.