NEUROMODULATORS RECEPTORS
\njˈuːɹəmˌɒdjʊlˌe͡ɪtəz ɹɪsˈɛptəz], \njˈuːɹəmˌɒdjʊlˌeɪtəz ɹɪsˈɛptəz], \n_j_ˈuː_ɹ_ə_m_ˌɒ_d_j_ʊ_l_ˌeɪ_t_ə_z ɹ_ɪ_s_ˈɛ_p_t_ə_z]\
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Cell surface receptors that bind signalling molecules released by neurons and convert these signals into intracellular changes influencing the behavior of cells. Neurotransmitter is used here in its most general sense, including not only messengers that act to regulate ion channels, but also those which act on second messenger systems and those which may act at a distance from their release sites. Included are receptors for neuromodulators, neuroregulators, neuromediators, and neurohumors, whether or not located at synapses.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.