NEUROGENIC THORACIC OUTLET SYNDROME
\njˌuːɹə͡ʊd͡ʒˈɛnɪk θɔːɹˈasɪk ˈa͡ʊtlɛt sˈɪndɹə͡ʊm], \njˌuːɹəʊdʒˈɛnɪk θɔːɹˈasɪk ˈaʊtlɛt sˈɪndɹəʊm], \n_j_ˌuː_ɹ_əʊ_dʒ_ˈɛ_n_ɪ_k θ_ɔː_ɹ_ˈa_s_ɪ_k ˈaʊ_t_l_ɛ_t s_ˈɪ_n_d_ɹ_əʊ_m]\
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A neurovascular syndrome associated with compression of the BRACHIAL PLEXUS; SUBCLAVIAN ARTERY; and SUBCLAVIAN VEIN at the superior thoracic outlet. This may result from a variety of anomalies such as a cervical rib (CERVICAL RIB SYNDROME), anomalous fascial bands, and abnormalities of the origin or insertion of the anterior or medial scalene muscles. Clinical features may include pain in the shoulder and neck region which radiates into the arm, PARESIS or PARALYSIS of brachial plexus innervated muscles, PARESTHESIA, loss of sensation, reduction of arterial pulses in the affected extremity, ISCHEMIA, and EDEMA. (Adams et al., Principles of Neurology, 6th ed, pp214-5).
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Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.