N 2 FLUORENYLACETAMIDE
\ˈɛn tˈuː flˈʊ͡əɹɪnˌɪlɐsˌɛtɐmˌa͡ɪd], \ˈɛn tˈuː flˈʊəɹɪnˌɪlɐsˌɛtɐmˌaɪd], \ˈɛ_n t_ˈuː f_l_ˈʊə_ɹ_ɪ_n_ˌɪ_l_ɐ_s_ˌɛ_t_ɐ_m_ˌaɪ_d]\
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A hepatic carcinogen whose mechanism of activation involves N-hydroxylation to the arylhydroxamic acid followed by enzymatic sulfonation to sulfoxyfluorenylacetamide. It is used to study the carcinogenicity and mutagenicity of aromatic amines.
By DataStellar Co., Ltd
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
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