N METHYL 4 PHENYLPYRIDINIUM
\ˈɛn mˈiːθa͡ɪl fˈɔː fˌiːna͡ɪlpˌɪɹɪdˈɪni͡əm], \ˈɛn mˈiːθaɪl fˈɔː fˌiːnaɪlpˌɪɹɪdˈɪniəm], \ˈɛ_n m_ˈiː_θ_aɪ_l f_ˈɔː f_ˌiː_n_aɪ_l_p_ˌɪ_ɹ_ɪ_d_ˈɪ_n_iə_m]\
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An active neurotoxic metabolite of 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE. The compound reduces dopamine levels, inhibits the biosynthesis of catecholamines, depletes cardiac norepinephrine and inactivates tyrosine hydroxylase. These and other toxic effects lead to cessation of oxidative phosphorylation, ATP depletion, and cell death. The compound, which is related to PARAQUAT, has also been used as an herbicide.
By DataStellar Co., Ltd
Word of the day
tinctura quininae ammoniata
- A preparation made by dissolving quinin sulphate in alcohol [Br. Ph.].
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