N METHYL 4 PHENYLPYRIDINE
\ˈɛn mˈiːθa͡ɪl fˈɔː fˌiːna͡ɪlpˈɪɹɪdˌiːn], \ˈɛn mˈiːθaɪl fˈɔː fˌiːnaɪlpˈɪɹɪdˌiːn], \ˈɛ_n m_ˈiː_θ_aɪ_l f_ˈɔː f_ˌiː_n_aɪ_l_p_ˈɪ_ɹ_ɪ_d_ˌiː_n]\
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An active neurotoxic metabolite of 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE. The compound reduces dopamine levels, inhibits the biosynthesis of catecholamines, depletes cardiac norepinephrine and inactivates tyrosine hydroxylase. These and other toxic effects lead to cessation of oxidative phosphorylation, ATP depletion, and cell death. The compound, which is related to PARAQUAT, has also been used as an herbicide.
By DataStellar Co., Ltd
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