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Definitions of N Acetylgalactosamine 4 sulfate Sulfatase

  1. An arylsulfatase that catalyzes the hydrolysis of the 4- sulfate groups of the N- acetyl- D- galactosamine 4- sulfate units of chondroitin sulfate and dermatan sulfate. A deficiency of this enzyme is responsible for the inherited lysosomal disease, Maroteaux- Lamy syndrome ( MUCOPOLYSACCHARIDOSIS VI). EC 3. 1. 6. 12.
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