Alphabet:
Loading...

Definitions of N Acetyl beta D hexosaminidase

  1.   An enzyme hydrolyzing terminal non reducing N acetyl D hexosamine residues in N acetyl beta D hexosaminides It acts on glucosides galactosides and several oligosaccharides Hexosaminidase A cleaves GM2 GA2 globosides and hexosamine oligosaccharides Deficiency of this isoenzyme causes TAY SACHS DISEASE Hexosaminidase B cleaves all the above substrates except GM2 A deficiency of both A and B causes SANDHOFF DISEASE The enzyme has also been used as a tumor marker to distinguish between malignant and benign disease EC 3 2 1 52