MYELIN BASIC PROTEINS
\mˈa͡ɪɪlˌɪn bˈe͡ɪsɪk pɹˈə͡ʊtiːnz], \mˈaɪɪlˌɪn bˈeɪsɪk pɹˈəʊtiːnz], \m_ˈaɪ_ɪ_l_ˌɪ_n b_ˈeɪ_s_ɪ_k p_ɹ_ˈəʊ_t_iː_n_z]\
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A group of 7 proteins produced from a single gene by alternate splicing found in central and peripheral nervous system myelin. The major basic protein (MBP) has long been of interest because it is the antigen, that, when injected into an animal, elicits a cellular immune response that produces the CNS autoimmune disease called experimental allergic encephalomyelitis (ENCEPHALOMYELITIS, ALLERGIC). In the peripheral nervous system, myelin basic protein 18.5 kD is often referred to as the P1 protein. (From Siegel et al., Basic Neurochemistry, 5th ed, p130, 133)
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