MULTICELLULAR TUMOR SPHEROID
\mˌʌltɪsˈɛljʊlə tjˈuːmə sfˈɛɹɔ͡ɪd], \mˌʌltɪsˈɛljʊlə tjˈuːmə sfˈɛɹɔɪd], \m_ˌʌ_l_t_ɪ_s_ˈɛ_l_j_ʊ_l_ə t_j_ˈuː_m_ə s_f_ˈɛ_ɹ_ɔɪ_d]\
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Spherical, heterogeneous aggregates of proliferating, quiescent, and necrotic cells in culture that retain three-dimensional architecture and tissue-specific functions. They represent an in-vitro model for studies of the biology of both normal and malignant cells. Generally the ability to form spheroids is a characteristic trait of malignant cells derived from solid tumors, though cells from normal tissues can also form spheroids. (From Bjerkvig, Spheroid Culture in Cancer Research, 1992, p4)
By DataStellar Co., Ltd
Word of the day
tinctura quininae ammoniata
- A preparation made by dissolving quinin sulphate in alcohol [Br. Ph.].