MUCOVISCIDOSES
\mjˈuːkəvˌɪsɪdˌə͡ʊzɪz], \mjˈuːkəvˌɪsɪdˌəʊzɪz], \m_j_ˈuː_k_ə_v_ˌɪ_s_ɪ_d_ˌəʊ_z_ɪ_z]\
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An inherited disease of exocrine glands, affecting most characteristically the pancreas, respiratory system, and sweat glands, usually beginning in infancy and typified by chronic respiratory infections, pancreatic insufficiency, and susceptibility to heat prostration. Cirrhosis of liver occurring in childhood is common and may produce portal hypertension, splenomegaly, and hypersplenism.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.