\mˈɔːɹ ˈɒfən ðɐn nˈɒt], \mˈɔːɹ ˈɒfən ðɐn nˈɒt], \m_ˈɔː_ɹ ˈɒ_f_ə_n ð_ɐ_n n_ˈɒ_t]\

Definitions of MORE OFTEN THAN NOT

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2006 - WordNet 3.0
By Princeton University
2011 - English Dictionary Database
By DataStellar Co., Ltd

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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