MOBILUNCUS CURTISII
\mˈə͡ʊbɪlˌʌnkəs kˈɜːtɪsˌɪa͡ɪ], \mˈəʊbɪlˌʌnkəs kˈɜːtɪsˌɪaɪ], \m_ˈəʊ_b_ɪ_l_ˌʌ_n_k_ə_s k_ˈɜː_t_ɪ_s_ˌɪ__aɪ]\
Word of the day
ATP Binding Cassette, Sub Family B Proteins
- A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.