MO1 GLYCOPROTEIN
\mˈə͡ʊ wˈɒn ɡlˈa͡ɪkəpɹˌə͡ʊtiːn], \mˈəʊ wˈɒn ɡlˈaɪkəpɹˌəʊtiːn], \m_ˈəʊ w_ˈɒ_n ɡ_l_ˈaɪ_k_ə_p_ɹ_ˌəʊ_t_iː_n]\
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An adhesion-promoting leukocyte surface membrane heterodimer. The alpha subunit consists of the CD11b antigen and the beta subunit of the CD18 antigen (ANTIGENS, CD18). The antigen, which is an integrin, functions both as a receptor for complement 3 and in cell-cell and cell-substrate adhesive interactions.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.