MITOSIS PROMOTING FACTOR
\ma͡ɪtˈə͡ʊsɪs pɹəmˈə͡ʊtɪŋ fˈaktə], \maɪtˈəʊsɪs pɹəmˈəʊtɪŋ fˈaktə], \m_aɪ_t_ˈəʊ_s_ɪ_s p_ɹ_ə_m_ˈəʊ_t_ɪ_ŋ f_ˈa_k_t_ə]\
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Protein kinase that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meiosis it induces immature oocytes to undergo meiotic maturation. In mitosis it has a role in the G2/M phase transition. Once activated by CYCLINS; MPF directly phosphorylates some of the proteins involved in nuclear envelope breakdown, chromosome condensation, spindle assembly, and the degradation of cyclins. The catalytic subunit of MPF is PROTEIN P34CDC2.
By DataStellar Co., Ltd
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
Nearby Words
- mitomycin c
- mitomycins
- mitoschisis
- mitoses
- mitosis
- Mitosis Promoting Factor
- mitosome
- mitosporic fungi
- mitotane
- mitotic
- mitotic apparatus