MINOR LYMPHOCYTE STIMULATORY ANTIGENS
\mˈa͡ɪnə lˈɪmfəsˌa͡ɪt stˌɪmjʊlˈe͡ɪtəɹˌi ˈantɪd͡ʒˌɛnz], \mˈaɪnə lˈɪmfəsˌaɪt stˌɪmjʊlˈeɪtəɹˌi ˈantɪdʒˌɛnz], \m_ˈaɪ_n_ə l_ˈɪ_m_f_ə_s_ˌaɪ_t s_t_ˌɪ_m_j_ʊ_l_ˈeɪ_t_ə_ɹ_ˌi_ ˈa_n_t_ɪ_dʒ_ˌɛ_n_z]\
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Endogenous superantigens responsible for inducing strong proliferative responses in T-cells in mixed lymphocyte reactions (see LYMPHOCYTE CULTURE TEST, MIXED). They are encoded by mouse mammary tumor viruses that have integrated into the germ line as DNA proviruses (MINOR LYMPHOCYTE STIMULATORY LOCI).
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.