MINOR LYMPHOCYTE STIMULATING DETERMINANTS
\mˈa͡ɪnə lˈɪmfəsˌa͡ɪt stˈɪmjʊlˌe͡ɪtɪŋ dɪtˈɜːmɪnənts], \mˈaɪnə lˈɪmfəsˌaɪt stˈɪmjʊlˌeɪtɪŋ dɪtˈɜːmɪnənts], \m_ˈaɪ_n_ə l_ˈɪ_m_f_ə_s_ˌaɪ_t s_t_ˈɪ_m_j_ʊ_l_ˌeɪ_t_ɪ_ŋ d_ɪ_t_ˈɜː_m_ɪ_n_ə_n_t_s]\
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Endogenous superantigens responsible for inducing strong proliferative responses in T-cells in mixed lymphocyte reactions (see LYMPHOCYTE CULTURE TEST, MIXED). They are encoded by mouse mammary tumor viruses that have integrated into the germ line as DNA proviruses (MINOR LYMPHOCYTE STIMULATORY LOCI).
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Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.