MINERALOCORTICOID RECEPTOR
\mˈɪnəɹˌaləkˌɔːtɪkˌɔ͡ɪd ɹɪsˈɛptə], \mˈɪnəɹˌaləkˌɔːtɪkˌɔɪd ɹɪsˈɛptə], \m_ˈɪ_n_ə_ɹ_ˌa_l_ə_k_ˌɔː_t_ɪ_k_ˌɔɪ_d ɹ_ɪ_s_ˈɛ_p_t_ə]\
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Cytoplasmic proteins that specifically bind mineralocorticoids and mediate their cellular effects. The receptor with its bound ligand acts in the nucleus to induce transcription of specific segments of DNA. Mineralocorticoids were named for their actions on extracellular electrolyte concentrations. The most important example is aldosterone.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.