MERKEL CELL TUMOR
\mˈɜːkə͡l sˈɛl tjˈuːmə], \mˈɜːkəl sˈɛl tjˈuːmə], \m_ˈɜː_k_əl s_ˈɛ_l t_j_ˈuː_m_ə]\
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A carcinoma arising from MERKEL CELLS located in the basal layer of the epidermis and occurring most commonly as a primary neuroendocrine carcinoma of the skin. Merkel cells are tactile cells of neuroectodermal origin and histologically show neurosecretory granules. The skin of the head and neck are a common site of Merkel cell carcinoma, occurring generally in elderly patients. (Holland et al., Cancer Medicine, 3d ed, p1245)
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Word of the day
Quinones
- Hydrocarbon rings which contain two moieties position. They can be substituted in any position except at the ketone groups.