MERKEL CELL CARCINOMA
\mˈɜːkə͡l sˈɛl kˌɑːsɪnˈə͡ʊmə], \mˈɜːkəl sˈɛl kˌɑːsɪnˈəʊmə], \m_ˈɜː_k_əl s_ˈɛ_l k_ˌɑː_s_ɪ_n_ˈəʊ_m_ə]\
Sort: Oldest first
-
A carcinoma arising from MERKEL CELLS located in the basal layer of the epidermis and occurring most commonly as a primary neuroendocrine carcinoma of the skin. Merkel cells are tactile cells of neuroectodermal origin and histologically show neurosecretory granules. The skin of the head and neck are a common site of Merkel cell carcinoma, occurring generally in elderly patients. (Holland et al., Cancer Medicine, 3d ed, p1245)
By DataStellar Co., Ltd
Word of the day
Procollagen Proline Dioxygenase
- mixed-function oxygenase that catalyzes hydroxylation prolyl-glycyl-containing-peptide, usually in protocollagen, hydroxyprolylglycyl-peptide. The enzyme utilizes molecular oxygen with a concomitant oxidative decarboxylation of 2-oxoglutarate to succinate. EC 1.14.11.2.