\mˈɛn θɹˈiː], \mˈɛn θɹˈiː], \m_ˈɛ_n θ_ɹ_ˈiː]\
Definitions of MEN 3
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A type of multiple endocrine neoplasia occurring as an isolated congenital presentation or as a distinct autosomal dominant disease. It is characterized by the 100% incidence of medullary thyroid carcinoma and frequent pheochromocytomas; patients seldom exhibit hyperparathyroidism. It is distinguished from MEN 2a by its characteristic physical appearance resulting from numerous neural defects including mucosal neuromas of the eyelids, lips, and tongue. The neural abnormalities also include widespread neurogangliomatosis of the gastrointestinal tract leading to abnormal gut motility. Treatment usually requires total thyroidectomy following evaluation for the presence of pheochromocytomas.
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- a threadlike extension of nerve cell Slender processes of neurons, especially the prolonged axons that conduct nerve impulses. One units trunk; it is axis process a neuron and medullated, i. e. white substance Schwann (myelin), medullated; either the medullated non-axis-cylinder or may not be surrounded by primitive sheath neurilemma, so that there are four forms of nerve-fibers.