MELACONISE

\mˈɛlɐkˌɒna͡ɪz], \mˈɛlɐkˌɒna‍ɪz], \m_ˈɛ_l_ɐ_k_ˌɒ_n_aɪ_z]\

Definitions of MELACONISE

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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