\mˈiː wˈɒn], \mˈiː wˈɒn], \m_ˈiː w_ˈɒ_n]\
Definitions of MEA 1
Sort: Oldest first
A rare syndrome characterized by hyperplasia and/or neoplasms of the pituitary, parathyroid glands, and pancreatic islets. Hyperparathyroidism occurs in 90% of the cases and is usually the first manifestation of the syndrome. The most frequent pancreatic manifestation is gastrinoma typically leading to Zollinger-Ellison Syndrome. The appearance of this condition has been limited to the loss of allelic heterozygosity at the 11q13 locus on the long arm of chromosome 11. Patients overall exhibit long survival times. Chemotherapy is rare and surgical management is generally dependent on the genetic expression in individual patients. (From Holland et al., Cancer Medicine, 3d ed, pp1169-72)
By DataStellar Co., Ltd
Word of the day
- The malarial gametocyte or any similar form in other protozoa. threadlike body, cast off from male element of malarial parasite, which fertilizes the female element.