\ˌɛmdˌiːˈɑː wˈɒn pɹˈə͡ʊtiːn], \ˌɛmdˌiːˈɑː wˈɒn pɹˈəʊtiːn], \ˌɛ_m_d_ˌiː__ˈɑː w_ˈɒ_n p_ɹ_ˈəʊ_t_iː_n]\
Definitions of MDR1 PROTEIN
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A 170 kD transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE).
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- The malarial gametocyte or any similar form in other protozoa. threadlike body, cast off from male element of malarial parasite, which fertilizes the female element.