MANUS EXTENSA

\mˈanəs ɛkstˈɛnsə], \mˈanəs ɛkstˈɛnsə], \m_ˈa_n_ə_s ɛ_k_s_t_ˈɛ_n_s_ə]\

Definitions of MANUS EXTENSA

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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