MANGINI'S REAGENT FOR ALKALOIDS

\maŋɡˈiːnɪz ɹɪˈe͡ɪd͡ʒənt fɔːɹ ˈalkɐlˌɔ͡ɪdz], \maŋɡˈiːnɪz ɹɪˈe‍ɪd‍ʒənt fɔːɹ ˈalkɐlˌɔ‍ɪdz], \m_a_ŋ_ɡ_ˈiː_n_ɪ_z ɹ_ɪ__ˈeɪ_dʒ_ə_n_t f_ɔː_ɹ ˈa_l_k_ɐ_l_ˌɔɪ_d_z]\

Definitions of MANGINI'S REAGENT FOR ALKALOIDS

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1916 - Appleton's medical dictionary
By Smith Ely Jelliffe

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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