M PHASE PROMOTING FACTOR
\ˈɛm fˈe͡ɪz pɹəmˈə͡ʊtɪŋ fˈaktə], \ˈɛm fˈeɪz pɹəmˈəʊtɪŋ fˈaktə], \ˈɛ_m f_ˈeɪ_z p_ɹ_ə_m_ˈəʊ_t_ɪ_ŋ f_ˈa_k_t_ə]\
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Protein kinase that drives both the mitotic and meiotic cycles in all eukaryotic organisms. In meiosis it induces immature oocytes to undergo meiotic maturation. In mitosis it has a role in the G2/M phase transition. Once activated by CYCLINS; MPF directly phosphorylates some of the proteins involved in nuclear envelope breakdown, chromosome condensation, spindle assembly, and the degradation of cyclins. The catalytic subunit of MPF is PROTEIN P34CDC2.
By DataStellar Co., Ltd
