LYMPHOCYTE FUNCTION ASSOCIATED ANTIGEN 1
\lˈɪmfəsˌa͡ɪt fˈʌŋkʃən ɐsˈə͡ʊsɪˌe͡ɪtɪd ˈantɪd͡ʒˌɛn wˈɒn], \lˈɪmfəsˌaɪt fˈʌŋkʃən ɐsˈəʊsɪˌeɪtɪd ˈantɪdʒˌɛn wˈɒn], \l_ˈɪ_m_f_ə_s_ˌaɪ_t f_ˈʌ_ŋ_k_ʃ_ə_n ɐ_s_ˈəʊ_s_ɪ__ˌeɪ_t_ɪ_d ˈa_n_t_ɪ_dʒ_ˌɛ_n w_ˈɒ_n]\
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A heterodimer molecule widely expressed on cells of hematopoietic origin. CD11a antigen comprises the alpha chain and the CD18 antigen (ANTIGENS, CD18) the beta chain. LFA-1 is a major receptor of T-cells, B-cells, and granulocytes. It mediates the leukocyte adhesion reactions underlying cytolytic conjugate formation, helper T-cell interactions, and antibody-dependent killing by natural killer cells and granulocytes. Intracellular adhesion molecule-1 (ICAM-1) has been defined as a ligand for LFA-1.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
Nearby Words
- lymphocyte cooperations
- lymphocyte count
- lymphocyte counts
- lymphocyte depletion
- lymphocyte derived neutrophil activating peptide
- Lymphocyte Function Associated Antigen 1
- lymphocyte function associated antigen 3
- lymphocyte homing receptors
- lymphocyte immunophenotyping
- lymphocyte immunophenotypings
- lymphocyte mediators