LYMPHOCYTE ACTIVATING DETERMINANTS
\lˈɪmfəsˌa͡ɪt ˈaktɪvˌe͡ɪtɪŋ dɪtˈɜːmɪnənts], \lˈɪmfəsˌaɪt ˈaktɪvˌeɪtɪŋ dɪtˈɜːmɪnənts], \l_ˈɪ_m_f_ə_s_ˌaɪ_t ˈa_k_t_ɪ_v_ˌeɪ_t_ɪ_ŋ d_ɪ_t_ˈɜː_m_ɪ_n_ə_n_t_s]\
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Endogenous superantigens responsible for inducing strong proliferative responses in T-cells in mixed lymphocyte reactions (see LYMPHOCYTE CULTURE TEST, MIXED). They are encoded by mouse mammary tumor viruses that have integrated into the germ line as DNA proviruses (MINOR LYMPHOCYTE STIMULATORY LOCI).
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