LUPUS ERYTHEMATOSUS DISSEMINATUS
\lˈuːpəs ˈɜːɹɪθˌɛmɐtˌɒsəs dɪsˈɛmɪnˌatəs], \lˈuːpəs ˈɜːɹɪθˌɛmɐtˌɒsəs dɪsˈɛmɪnˌatəs], \l_ˈuː_p_ə_s ˈɜː_ɹ_ɪ_θ_ˌɛ_m_ɐ_t_ˌɒ_s_ə_s d_ɪ_s_ˈɛ_m_ɪ_n_ˌa_t_ə_s]\
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A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.
Nearby Words
- lupus discreta
- lupus discretus
- lupus disseminatus
- lupus erythematodes, lupus erythematosus
- lupus erythematosus
- Lupus Erythematosus Disseminatus
- lupus erythematosus panniculitides
- lupus erythematosus panniculitis
- lupus erythematosus profundus
- lupus erythematosus, chronic cutaneous
- lupus erythematosus, cutaneous, chronic