LOSS GIVEN DEFAULT (LGD)
\lˈɒs ɡˈɪvən dɪfˈɒlt ˌɛld͡ʒˌiːdˈiː], \lˈɒs ɡˈɪvən dɪfˈɒlt ˌɛldʒˌiːdˈiː], \l_ˈɒ_s ɡ_ˈɪ_v_ə_n d_ɪ_f_ˈɒ_l_t__ ˌɛ_l_dʒ_ˌiː_d_ˈiː]\
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.