LOCALIZATION RELATED EPILEPSIES
\lˌə͡ʊkəla͡ɪzˈe͡ɪʃən ɹɪlˈe͡ɪtɪd ˈɛpɪlˌɛpsɪz], \lˌəʊkəlaɪzˈeɪʃən ɹɪlˈeɪtɪd ˈɛpɪlˌɛpsɪz], \l_ˌəʊ_k_ə_l_aɪ_z_ˈeɪ_ʃ_ə_n ɹ_ɪ_l_ˈeɪ_t_ɪ_d ˈɛ_p_ɪ_l_ˌɛ_p_s_ɪ_z]\
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Conditions characterized by recurrent paroxysmal neuronal discharges which arise from a focal region of the brain. Partial seizures are divided into simple and complex, depending on whether consciousness is unaltered (simple partial seizure) or disturbed (complex partial seizure). Both types may feature a wide variety of motor, sensory, and autonomic symptoms. Partial seizures may be classified by associated clinical features or anatomic location of the seizure focus. A secondary generalized seizure refers to a partial seizure that spreads to involve the brain diffusely. (From Adams et al., Principles of Neurology, 6th ed, pp317)
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.