LAPIS OPHTHALMICUS

\lˈapiz ɒfθˈalmɪkəs], \lˈapiz ɒfθˈalmɪkəs], \l_ˈa_p_i_z ɒ_f_θ_ˈa_l_m_ɪ_k_ə_s]\

Definitions of LAPIS OPHTHALMICUS

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Platidiam

  • An inorganic water-soluble platinum complex. After undergoing hydrolysis, it reacts DNA produce both intra interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity cisplatin correlates with cellular arrest in G2 phase cell cycle.
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