\lˈandɪɡˌandmən], \lˈandɪɡˌandmən], \l_ˈa_n_d_ɪ_ɡ_ˌa_n_d_m_ə_n]\

Definitions of LANDEGANDMAN

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1910 - Black's Law Dictionary (2nd edition)
By Henry Campbell Black

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ATP Binding Cassette, Sub Family B Proteins

  • A subfamily transmembrane the superfamily TRANSPORTERS that closely related in GLYCOPROTEIN. When overexpressed, function as dependent efflux pumps able extrude lipophilic drugs, especially ANTINEOPLASTIC AGENTS, from cells causing resistance (DRUG RESISTANCE, MULTIPLE). Although P-Glycoproteins share functional similarities to MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS they are two distinct subclasses of ATP-BINDING CASSETTE TRANSPORTERS, and have little sequence homology.
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