L TYPE VOLTAGE DEPENDENT CALCIUM CHANNELS
\ˈɛl tˈa͡ɪp vˈə͡ʊltɪd͡ʒ dɪpˈɛndənt kˈalsi͡əm t͡ʃˈanə͡lz], \ˈɛl tˈaɪp vˈəʊltɪdʒ dɪpˈɛndənt kˈalsiəm tʃˈanəlz], \ˈɛ_l t_ˈaɪ_p v_ˈəʊ_l_t_ɪ_dʒ d_ɪ_p_ˈɛ_n_d_ə_n_t k_ˈa_l_s_iə_m tʃ_ˈa_n_əl_z]\
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Long-lasting voltage-gated CALCIUM CHANNELS found in both excitable and nonexcitable tissue. They are responsible for normal myocardial and vascular smooth muscle contractility. Five subunits (alpha-1, alpha-2, beta, gamma, and delta) make up the L-type channel. The alpha-1 subunit is the binding site for calcium-based antagonists. Dihydropyridine-based calcium antagonists are used as markers for these binding sites.
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Nearby Words
- l type vdcc alpha 1 subunit
- l type vdcc alpha 2 subunit
- l type vdcc beta subunit
- l type vdcc delta subunit
- l type vdcc gamma subunit
- L Type Voltage Dependent Calcium Channels
- l tyrosine
- l valine
- l'aquila
- l'art pour part
- l'enfant