KERNICTERUS
\kˈɜːnɪktəɹəs], \kˈɜːnɪktəɹəs], \k_ˈɜː_n_ɪ_k_t_ə_ɹ_ə_s]\
Definitions of KERNICTERUS
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an abnormal accumulation of bile pigment in the brain and other nerve tissue; causes yellow staining and tissue damage
By Princeton University
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an abnormal accumulation of bile pigment in the brain and other nerve tissue; causes yellow staining and tissue damage
By DataStellar Co., Ltd
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A term used pathologically to describe BILIRUBIN staining of the BASAL GANGLIA; BRAIN STEM; and CEREBELLUM and clinically to describe a syndrome associated with HYPERBILIRUBINEMIA. Clinical features include athetosis, MUSCLE SPASTICITY or hypotonia, impaired vertical gaze, and DEAFNESS. Nonconjugated bilirubin enters the brain and acts as a neurotoxin, often in association with conditions that impair the BLOOD-BRAIN BARRIER (e.g., SEPSIS). This condition occurs primarily in neonates (INFANT, NEWBORN), but may rarely occur in adults. (Menkes, Textbook of Child Neurology, 5th ed, p613)
By DataStellar Co., Ltd
Word of the day
Quinones
- Hydrocarbon rings which contain two moieties position. They can be substituted in any position except at the ketone groups.