KAINATE RECEPTORS
\kˈa͡ɪne͡ɪt ɹɪsˈɛptəz], \kˈaɪneɪt ɹɪsˈɛptəz], \k_ˈaɪ_n_eɪ_t ɹ_ɪ_s_ˈɛ_p_t_ə_z]\
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Cell surface proteins that bind glutamate and directly gate ion channels. Kainic acid receptors were originally discriminated from other glutamate receptors by their affinity for the agonist kainic acid. Activation of kainic acid receptors is generally excitatory to cells. Subtypes have been cloned, and for some the traditional distinction from AMPA receptors may not apply.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.