ISLET CELLS
\ˈa͡ɪlət sˈɛlz], \ˈaɪlət sˈɛlz], \ˈaɪ_l_ə_t s_ˈɛ_l_z]\
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Irregular microscopic structures, varying from a few to hundreds of cells, scattered throughout the pancreas and comprising its endocrine portion. There are three cell types: alpha, secreting glucagon; beta, secreting insulin; and delta (D CELLS), secreting somatostatin.
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Proto Oncogene Proteins c erbB 2
- cell surface protein-tyrosine kinase that is found to be overexpressed in significant number adenocarcinomas. It has extensive homology can heterodimerize EGF EPIDERMAL GROWTH FACTOR), 3 receptor (RECEPTOR, 3) and the 4 receptor. Activation of erbB-2 receptor occurs during heterodimer formation with a ligand-bound erbB family members. EC 2.7.11.-.